Female abnormalities are due to variations in the number of X chromosomes. Their ovaries do not develop normally and they do not ovulate. The few oöcytes. Sex chromosome disorders belong to a group of genetic conditions that are caused or affected by the loss, damage or addition of one or both sex chromosomes (also called gonosomes). In humans this may refer to: 45, X, also known as Turner syndrome. 47, XXY, also known as Klinefelter syndrome.